The song will premiere on the 50th anniversary of the James Bond film franchise's debut, Friday, Oct. 5 at 0:07 in London time (or the less thematically appropriate 7:07 p.m. ET on Oct. 4). Fans can pre-order via iTunes now, then download the track after it officially debuts on Adele's website.
The "21" singer enlisted Paul Epworth to produce the track, which features a 77-piece orchestra and marks her first release since "21" debuted in January 2011.
"I was a little hesitant at first to be involved with the theme song for 'Skyfall,'" Adele said in a statement. "There's a lot of instant spotlight and pressure when it comes to a Bond song. But I fell in love with the script and Paul had some great ideas for the track and it ended up being a bit of a no brainer to do it in the end."